Male Fertility and Infertility

This contemporary account of male fertility provides a much-needed bridge between those seeking to understand the subject from an evolutionary and biological perspective, and those with clinical responsibility for the investigation and treatment of male infertility. Accordingly, the first half of the book deals with evolutionary aspects of male reproduction and sperm competition, sperm production and delivery in man and other animals, spermatogenesis and epididymal function, sperm transport in the female tract, and the apparent decline in human sperm count. The second part of the book puts greater emphasis on clinical problems and opens with a discussion of ICSI, including its value and limitations. This is followed by a review of modern developments in the genetics of male infertility and proceeds to a further chapter on the role of surgical procedures in the treatment of male infertility. The contributors provide a critical review of semen analysis and a full description of the molecular techniques now being used in preimplantation diagnosis and in the study of mitochondrial inheritance. This volume, written by an international team of authors, illustrates the breadth of vision needed to tackle the problem of male infertility.